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Key points to consider include fatigue, concentration difficulties, and emotional flatness

For example, short acting insulin or basal insulin adjustments can address gaps while oral agents are held

In this scenario, GHK-Cu alone is the scientifically correct choice

Generally, appetite suppression and early blood glucose improvements may be noticed within the first 12 weeks, whilst measurable weight loss typically becomes apparent after 48 weeks

Some patients benefit from extending the time at a lower dose or reducing from 14 mg to 7 mg (under medical supervision) to allow better tolerance before re-escalating