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[49], with permission from Elsevier
Now, new research suggests there may be another benefit: The combination of a GLP-1 drug with menopausal hormone treatment (MHT) may aid in weight loss more than a GLP-1 taken alone, and it may provide some cardiovascular benefits, too
Your provider may adjust timelines if you experience side effects or plateau in weight loss
If this is a new pen from the refrigerator, let it warm to room temperature for about 15-20 minutes
[6] Proposed mechanisms for cardiovascular benefits of incretin-based therapies include: Vascular effects : Improved endothelial function and reduced arterial stiffness Anti-inflammatory actions : Decreased systemic inflammation and oxidative stress Metabolic improvements : Enhanced insulin sensitivity and reduced hepatic glucose production Hemodynamic changes : Blood pressure reduction, though with modest increases in heart rate Renal protection : Reduced albuminuria and preservation of kidney function The cardiovascular benefits appear partially independent of weight loss itself, suggesting potential cardioprotective properties of incretin pathway activation
Semaglutide: Well-characterized GI side effect profile over 7+ years
