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While clinical interactions have not been documented, combining multiple compounds that affect similar pathways increases unpredictability

Even the maximum 15mg dose requires only 37.5 units, which is barely a third of a full 1 ml syringe

Tracking any symptoms, timing, and dose allows early detection of adverse reactions

One of the hallmarks of RA is persistent synovitis, which is associated with the local infiltration of various immune cells and excessive inflammatory mediators [48]

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Pathway enrichment analysis of these differentially prevalent metabolites revealed significant perturbations in metabolic networks including branched-chain aminoacids degradation, glutathione metabolism, threonine and 2-oxobutanoate degradation, gluconeogenesis, pyruvate metabolism, and glycine and serine metabolism (Figure S5)