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Because semaglutide is once weekly, a shift of even 6 to 8 hours in injection timing creates zero clinical issues

High Dose (10 mcg/kg): Typically reserved for acute/severe injuries or advanced orthopedic conditions

The early patent expiration creates a unique competitive environment for Canadian consumers and healthcare systems

For patients with persistent reflux symptoms despite 8 weeks of PPI therapy or those with alarm features, referral to gastroenterology for upper endoscopy may be warranted, consistent with American College of Gastroenterology guidelines

Even walking for 30 minutes, three to five times a week can make a big difference

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