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Reducing glutathione production in lymphoma cells, either through pharmacological inhibition of glutamate cysteine ligase (GCL), the enzyme catalyzing the rate-limiting step in glutathione biosynthesis, or via knockdown of GCLC , the GCL catalytic subunit, sharply decreased cell growth in 3D gels and xenografts

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Figure 2 Statistical Analysis The obtained data concerning the testicular hemodynamics (PSV, EDV, RI, PI, and TAMAX), TE and PH, and biochemical analysis (NOMs and TAC) are presented as means SEM

There will be ample opportunity for this as more combinations are developed