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Rapid acetylators were competent in isoniazid acetylation but the drug was cleared less efficiently in the slow acetylator group, which resulted in elevated serum concentration and led to adverse neurologic side effects due to an accumulation of unmetabolized drug (Brockton et al., 2000)
Partridge, M
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The expression of iNOS was increased, while the nNOS expression was decreased in the epidermal skin lesions
The pharmacokinetic values are approximate and come from the pharmacological literature on GHRH analogs and GH secretagogues
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