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The drug, following a favorable vote from the Endocrinologic and Metabolic Drugs Advisory Committee, was approved in December 2014 by the U.S

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Co-administration with sildenafil enhanced erectile activity compared to sildenafil alone, offering a potential alternative for patients with inadequate single-therapy responses (6)

Total direct costs were estimated to be GBP 42 064 with immediate oral semaglutide use and GBP 40 641 with a 2-year delay, leading to a GBP 1423 incremental increase in the immediate oral semaglutide arm over patients lifetimes (figure 1)

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