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Enzymatic conjugation of chlorambucil with glutathione by research-subject glutathione S-transferases and inhibition by ethacrynic acid

Kalff, M

In male mouse models of amyloidosis, such as APP/PS1 and TASD41 (hAPP751 with the London V717I9/Swedish double mutation K670M/N671L), aggressive behavior correlates with a progressive increase in amyloid plaque size and density in cortical, hippocampal, and amygdala regions (Morgastrern et al., 2018)

P -values derived from a Wilcoxon rank-sum test, followed by adjustment by the BenjaminiHochberg procedure to correct for multiple testing

Low glutathione has been linked to shallow, restless sleep, particularly because of its role in reducing oxidative stress in the brain