It upregulates genes involved in collagen synthesis (COL1A1, COL3A1, COL5A1), extracellular matrix remodeling (decorin, fibromodulin), and antioxidant defense (superoxide dismutase, glutathione peroxidase) while simultaneously suppressing genes associated with inflammation (IL-6, TNF-alpha), fibrinogen production, and tissue destruction (several MMPs)
Below is the full comparison table first, then short notes on each medication and the emerging pipeline, so you can see exactly how the whole class fits together
Multi-omics approaches provide a more comprehensive understanding of the vaginal microbiome and its interactions with HPV
Compounded medicines dont have the same serialization (DSCSA) as generic/branded medicines, which means that they are more difficult to track and recall if they harm patients
may vary elsewhere
In clinical trials, it was reported that 14mg doses had more side effects on patients than 7mg doses