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[66] GABA enhances the catabolism of serotonin into N -acetylserotonin (the precursor of melatonin) in rat pineal glands (removed from the body, ex vivo )
It is also a primary site of drug detoxification, which relies heavily on GSH availability 28
182 GuoC.SunL.ChenX.ZhangD
PMID: 6124382.
Gq/11 interacts with PLC, which may split a fat-like molecule, phosphatidylinositol 4,5-bisphosphate (PIP2), into two messaging molecules: IP3 (Inositol trisphosphate) and DAG (Diacylglycerol)
It works by inhibiting melanin production, leading to a more even skin tone, and reducing hyperpigmentation
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