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Interesting concept suggesting combination of GLP-1 receptor agonists and centrally acting fixed combination of naltrexone and bupropion Mechanistically,m it may make sense due to different pathways that are trargeted Gut HormoneHedonic Brain Axis and eating behaviors may be specifically targeted by naltrexone and bupropion combination thereby complementing the effects of GLP-1-based therapies #obesity #weightreduction #glp1receptoragonists #semaglutide #tirzepatide #naltrexin #bupropion #hedonicbrainaxis Martin Haluzks Post : Very interesting review just published in Obesity Science and Practice by Alex Miras and Muzamil Hussain
Therefore, patients should be aware of their total daily intake from all sources, including food and other supplements, and follow product labelling for appropriate use
10.1530/joe-13-0221 161
However, if weight loss is the main objective, other GLP1 options like Wegovy might provide superior results due to higher dosing for obesity management
I have tried everything from gels, sprays, lozenges, gum, Salivary Pacemakers -implantable and removable, pilocarpines, and cevimelines
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