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Oxidative stress in multiple sclerosis: central and peripheral mode of action

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Even in the absence of DsbA, roGFP2, exported to the periplasm, was fully oxidized, suggesting the presence of an alternative system for the introduction of disulfide bonds into exported proteins

2023;133:e169131

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Cystine starvation alone reduced GSH and was not further aggravated by deprivation of other amino acids and supplementation of cystine alone was sufficient to restore GSH level in the absence of other amino acids (Fig