Viability assays can show whether cells remain metabolically active under experimental conditions
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A: Multiple pathways: GH receptor upregulation, nitric oxide system modulation, VEGF-promoted angiogenesis, and direct inflammatory cytokine interaction
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Receptors have time to reset between signals, potentially maintaining sensitivity over longer treatment periods
The researchers concluded that AOD-9604 represents a promising fat-reducing alternative to growth hormone therapy without its associated metabolic risks, particularly regarding glucose regulation and IGF-1 elevation