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Current research shows a possible association rather than confirmed causation, as patients taking semaglutide often have underlying risk factors including obesity and metabolic syndrome
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Dong S, Sun C
The weight loss and insulin sensitivity improvements associated with orforglipron would be expected to significantly reduce the risk of progression from prediabetes to overt type 2 diabetes
These can include nausea, vomiting, diarrhoea, and abdominal cramps
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