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These proposed mechanisms sound compelling, but it is vital to remember that these effects are mostly observed in rodent models or cell cultures, not in humans

In hypertension models, GLP-1 RAs exert beneficial effects through multiple mechanisms including vascular vasodilation, diuresis, decreased sympathetic activity in the central nervous system, and reduced blood pressure variability (BPV) [15]

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Obesity and the polycystic ovary syndrome

10.1016/j.brainres.2013.07.018 Brain Res