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Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist

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Published preclinical data in rodents suggests doses equivalent to 200mg+ in humans produce off-target effects on folate metabolism and S-adenosylmethionine (SAMe) pools

Injectable forms, which require a prescription, are 100% bioavailable but should be administered under medical supervision: 2 3

Conversely, infusions may suit individuals aiming for long-term wellness and preventive health care

Still, the preservative has limits