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The inclusion criteria were as follows: the study type must be an RCT

Dai ZH, Zhou CC, Yu CY, Qian CJ, Jin SQ, Du SQ

Heavy metal detoxification: Chelation and cellular glutathione replenishment are two strategies to improve natural detoxification pathways in toxicological therapy

GSH antioxidants can act as a metal chelator and radical quencher

The 28-day bacteriostatic window typically ends before coring becomes a serious issue, but high-frequency dosing protocols (daily or twice-daily) can hit the penetration limit before the chemical stability window closes

Unfortunately, quality studies that demonstrate the benefits of IV glutathione are based mainly on animal studies since few studies demonstrate its benefits conducted on humans