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administration of oxytocin, which inhibits food intake via activation of vagal afferents 27 , exerted its anorexigenic effect in Glp1r KO and WT mice to similar extents (Fig

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The microsomes were incubated with 500 M solutions of Dihexa, piroxicam, verapamil, and 7-ethoxycoumarin, as controls for low, moderate, and highly metabolized compounds, respectively, in 0.1 M Tris buffer with an NADPH-regenerating system at 37C