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Class 1 is for traumatic injuries

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This commonly happens at L4-L5 or L5-S1 levels

The committee said the result of that study could limit the systemic toxicity of KPV applied topically to the skin. 4

Copper itself is a comparatively weak skin sensitizer a 2014 review (PMID 25098945) reported positive copper patch-test reactions in roughly 3.8% of tested subjects so contact allergy is possible but uncommon

Overview of the complex figure test and its clinical application in neuropsychiatric disorders, including copying and recall