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Tirzepatide: the GIP potentiation effect Tirzepatide is a 39-amino-acid peptide biased toward GIP (5 higher affinity for GIPR than GLP-1R)

From this, results will then last on average for two years

A trial showing 8% mean body-fat reduction in a European cohort should not be assumed to replicate identically in a Japanese cohort without attention to ADRB3 allele distribution

This cycle may contribute to continued blood-vessel irritation and plaque progression

10.1007/s00125-017-4330-3 39