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The chief drugs implicated in druginduced melanosis are the antimalarials, including chloroquine, hydroxychloroquine, and quinacrine (Figure 515)
They can scavenge reactive molecules, encourage cellular repair, and adjust signaling pathways associated with reproduction
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This can result in a reduced need for thyroid hormone replacement, particularly in patients who initially required higher doses due to obesity-related factors like increased inflammation or altered hormone metabolism
Management of gout and hyperuricemia: Multidisciplinary consensus in Taiwan
[online] Available at: [Accessed 30 Aug
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