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In a phase 2 clinical trial conducted on an obese population, over a 26-week period, patients who were administered a dose range of efinopegdutide from 5 mg to 10 mg experienced a weight reduction of up to 11.8%

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l , SMART1 promoted ubiquitination of Smurf1 (SMART1: 0.2 M, 1 M, 5 M, SMART1-L: 1 M or Poma: 1 M)

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In the context of shared mechanistic pathways relevant to thyroidbrain interactions, these data remain biologically informative, yet they also highlight a critical gap in thyroid-specific primary research

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