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However, individual responses vary considerably, with some patients experiencing more modest results

This is clearly not sufficient to rescue the reward and metabolic phenotype in males, although we can hypothesize that simultaneous GLP-1R knockdown in both of these sites may produce an even more pronounced reward phenotype in males

Rosta, K

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Current guidelines recommend determining, assessing and pursuing regularly an HbA1c goal on an individual basis, given the strong predictive value for diabetes complications