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adults: Nearly half of overweight Americans report having taken a GLP-1 for weight loss, including many who are currently using the medication

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The article says these are usually required first

I still have a ton here, so Ill keep experimenting, but I wanted to share my N=1

10.1016/j.neuint.2016.12.012 18 BilleciL.CallaraA

Amylin analogues like cagrilintide act directly on amylin receptors in the brainstem , producing satiety through the area postrema