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While medications maintain sustained, supraphysiologic hormone levels and typically produce significant weight reduction and HbA1c decreases, food-stimulated GLP-1 is released in brief pulses after meals and rapidly degraded within minutes, resulting in smaller metabolic improvements

For years, the biggest shifts in beverage alcohol have been driven by consumer preference: premiumization, ready-to-drink cocktails, and more recently, non-alcoholic alternatives

And that's without accounting for the biggest shoe to drop in 2026: the coming of generic semaglutide (found in Ozempic and Wegovy from Novo Nordisk)

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The most common semaglutide side effects and tirzepatide side effects are gastrointestinal symptoms

What does that mean