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ThTP-dependent phosphorylation of rapsyn regulates ACh neurotransmission, as rapsyn is a scaffolding protein of the post-synaptic membrane of neuromuscular junctions, specifically associated with nicotinic ACh receptors (232)
Yes, for some, no, for others
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Factors such as age and associated medical conditions can also impact individual response to TB-500
Overall, our results have shown that the acquired dual elevations in NOX activity and glutathione pool create a therapeutic vulnerability in oncogenic RAS-transformed cancer cells
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