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GLP-1 is a naturally occurring human hormone, released in the small intestine in response to food, that helps stabilize glucose levels

This further impairs the methylation process and, as a result, significantly affects DNA methylation 13

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In Ringer solution, when the hematocrit was adjusted to 4%, PS exposure was not significantly different, although it was around half the level of PS exposure seen in the 0.4% hematocrit condition

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Other treatments that are synthetically lethal with the inhibition of GLS include GLUT2q1 inhibition, mTOR inhibition, and ATF4 activation [44]