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For example, iron overload promotes the inflammatory response in macrophages by increasing the ability of 5-LOX to bind to the nuclear membrane

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Unlike H1 and H2 histamine receptor antagonists, which showed inconsistent results across the different animal models, BPC-157 had a strong beneficial effect in both rats and mice

Oxidative stress and redox imbalance : Accumulation of reactive oxygen species (ROS) and a decrease in antioxidant activity disrupts mitochondrial functions and promotes cellular damage

These are considered critical antioxidants for their potential roles in facilitating tissue repair by protecting cells from oxidative stress

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