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GLP-1 Drug Shortages and Compounding July 2024 IPD has released a new podcast episode, GLP-1 Drug Shortages and Compounding," where Alyssa Guest, PharmD, discusses the glucagon-like peptide-1 (GLP-1) drugs and how interest in weight loss, viral social media posts, celebrity endorsements, illegitimate compounding, and drug shortages have all impacted access to GLP-1s
That can help with glycemic control and can hold back how hungry you feel
However, what works best depends on individual health factors and responses, which is why professional medical guidance is essential
Note: As with any significant change in fiber or probiotic intake, some individuals experience temporary gas or digestive adjustment in the first few days
If other causes of eosinophilia are identified (asthma, allergies, collagen vascular disease, parasitic infection, neoplasm), treat these and continue clozapine
Orlistat has traditionally been a first-line option due to its established safety profile and availability, though its modest efficacy (typically 3-5% additional weight loss beyond lifestyle intervention) and gastrointestinal side effects limit its appeal
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