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NOX4 produces H 2 O 2 in the perinuclear region within thyroid cell, thus, when being in excess it can induce DNA damage, and also in such intracellular compartments as mitochondria and endoplasmic reticulum [139] (see also Fig

Bacteriostatic diluent in the other chamber

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To prevent recurrent DVT and PE after initial treatment

Although these drugs have significant effects in antitumor and other disease treatments, due to their lack of selectivity, they may also cause damage to normal cells, leading to side effects and drug resistance [474]