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Oral supplementation of vitamin C notably alleviates symptoms like gingival bleeding and swelling, promoting the overall health of periodontal tissues ( Studies show that vitamin C usefully alleviates clinical symptoms and the risk of disease progression in periodontitis through alleviating oxidative pressure and inflammatory mediator release ( Besides, local application of vitamin C in the oral environment has also been studied for its antioxidant and anti-inflammatory properties in alleviating the severity of gingival inflammation ( 4.1.2 Effects of vitamin E application Vitamin E, as a fat-soluble antioxidant, displays vital advantages following oral supplementation, in particular in the protection and improvement of periodontal tissues (Nagata, 2013)

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