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doi: 10.1016/j.actatropica.2019.105306 215 GoodridgeHSWolfAJUnderhillDM
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Centenarians have plasma MOTS-c levels resembling those of people decades younger, suggesting preserved mitochondrial signaling is a feature of exceptional aging
Patients were grouped based on whether they regained weight, maintained their weight loss, or experienced further weight reduction
In the SURMOUNT-1 trial, which enrolled 2,539 adults with obesity or overweight, participants achieved significant weight reduction across all tirzepatide dose groups (5 mg, 10 mg, and 15 mg weekly)
