This medication is not recommended for people with preexisting conditions, such as glaucoma, hyperthyroidism, or a history of extensive cardiovascular disease
Furthermore, in DPP-IV deficient mice, increase in the percentage of splenic CD+ cells and NKT cells as well as increase in macrophages was observed (Detel et al
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With increased utilization there have been concerns about potential risks
GLP-1 therapy raised yearly health care costs by about $7,000 in the first year and $4,200 in the second year compared to the control group