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Kidney damage There are reports of acute kidney injury and worsening chronic renal failure in people who were treated with semaglutide
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Compounded GLP-1 medications are prepared by licensed compounding pharmacies and must be sourced from FDA-regulated active pharmaceutical ingredient (API) suppliers
In them, patients taking the highest weekly dose (15 mg) of Zepbound lost 48 pounds on average, while those taking the lowest dose (5 mg) lost on average 34 pounds (compared to 7 pounds on placebo) over 72 weeks
Further studies are needed to investigate the bone impact of GLP-1Ra, dual- and triple-receptor agonists for GLP-1, glucose-dependent insulin releasing polypeptide (GIP), and glucagon in PwO
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