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Correlation of the in vitro biotransformation of H3B-6527 in dog and human hepatocytes with the in vivo metabolic profile of (14)C-H3B-6527 in a dog mass balance study

Powell, R

Moreover, the concept of proteostasis resilience, the capacity of cells and tissues to preserve proteome integrity under sustained stress, is emerging as a powerful unifying lens to understand disease vulnerability, progression, and therapeutic responsiveness

doi 10.1186/s12876-023-02716-4 88 AzmyNabeh OIshak AttallahMElSayed ElGawharyN

However, the uneven surface and clear boundaries of the regenerated tissues revealed their limited recovery capability

On the other hand, it is also clear that prolonged LC supplementation elevates fasting plasma TMAO [16,17,18, 58, 59], compound supposed to be pro-atherogenic [61]