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If pancreatitis is suspected (severe, persistent abdominal pain, particularly if radiating to the back, accompanied by nausea and vomiting), the GLP-1 medication should be discontinued immediately and urgent medical assessment sought

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The meta-analysis by Wang and colleagues 137 included an unpublished trial (NCT00845507 145 ) that was not part of the more recent meta-analysis by Khaity and colleagues 134

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Table of Contents: How quickly does semaglutide GLP-1 start suppressing appetite

Evidence boundary BPC-157 has no published human Phase 2 or Phase 3 dose-finding trial