The enthusiasm surrounding these molecules both the naturally occurring kind as well as the synthetic variety is that they can be engineered to target specific biological processes involved in tissue regeneration, bone healing, gut health and sexual function, among many others
Rather than isolating a single mechanism, this formula allows researchers to examine complementary pathways simultaneously
What they did: They transected the quadriceps (front thigh) of rats and divided them into three groups: Control, no drugs Dexamethasone, a potent corticosteroid that is known to impair healing Dexamethasone + BPC-157 What they found: Dexamethasone group: 50 % worse healing than control (confirmed negative effect of steroids) Dexamethasone + BPC-157 group: healing at the level of controls without steroids Why it matters: This is a highly clinically relevant finding
[112] Furthermore, this assay requires overnight incubation and may give false results if any inactive vitamin B 12 analogues are present in the foods
This is relevant for osteoarthritis and joint regeneration research
In response to the challenges faced, multiple approaches, pathways, and strategies are under investigation e.g., senolytics and senomorphics