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2 Materials and methods 2.1 Ethics and regulatory compliance We designed our study in accordance with the ARRIVE guidelines (Percie du Sert et al., 2020) and conducted all experiments in compliance with IACUC regulations and the National Research Councils Guide for the Care and Use of Laboratory Animals, with prior approval from the Texas A&M University IACUC (protocol number 2023-0186)

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Regulatory and Legal Status The regulatory landscape differs substantially between these compound classes