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Animal studies indicate dose-dependent effects, with toxic doses possibly affecting copper metabolism or interacting with embryonic development in hypersensitive models, warranting caution during pregnancy
Summary: Vitamin B12 injections for pernicious anaemia deliver hydroxocobalamin intramuscularly to bypass malabsorption caused by lack of intrinsic factor, rapidly correcting deficiency and preventing neurological damage
Dynamic regulation of epigenetic demethylation by oxygen availability and cellular redox
The primary mechanism of action involves B12s essential role in several enzymatic processes crucial for health
doi:10.1016/j.jaad.2016.04.051
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