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For menopausal women, tirzepatide may have an edge over semaglutide because GIP receptors are found in adipose tissue and may directly influence fat metabolism beyond what GLP-1 alone can achieve

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Long-term safety evaluation in APP/PS1 mice during the 3-month treatment also revealed no toxicity

Immunocompromised status : Including HIV/AIDS, active cancer treatment, immunosuppressive medication, or congenital immune deficiencies

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