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It must come from diet or supplementation
The AUGUSTUS trial (N=4,614) showed that adding aspirin to apixaban in patients with atrial fibrillation and recent acute coronary syndrome increased bleeding events from 7.3% to 10.9% over 6 months (HR 1.89, 95% CI 1.59 to 2.24) [12]
This may not sound like a big deal but it is
Significant pain reduction typically occurs by weeks 2-3, with maximum benefits often achieved by week 6-8
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