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MEOS uses a different enzyme (Cytochrome P450 2E1 - CYP2E1) to metabolize ethanol, but still creates toxic acetaldehyde

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I ordered from a Canadian supplier, learned to reconstitute on my own, and mapped out my titration schedule before I ever drew my first dose

Four years later in 2021, the FDA gave the green light to another brand-name drug with semaglutide as the active ingredient: Wegovy, which was (and still is) approved for chronic weight management in people with either obesity (body mass index (BMI) of 30 or greater) or overweight with at least one weight-related medical condition, such as type 2 diabetes or high blood pressure

Yet GLP-1 receptors are not expressed on liver cells, suggesting that the drugs have an indirect effect: There are no GLP-1 receptors expressed in hepatocytes

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