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Stress-induced cortisol response and fat distribution in women

DOI: 10.1186/s40360-017-0172-3 [Google Scholar] Li W, Cui M, Wei Y, Kong X, Tang L, Xu D

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Research demonstrates that postmenopausal women experience a 9% decrease in total 24-hour energy expenditure and a 30% reduction in spontaneous physical activity energy expenditure.[1] The metabolic consequences are profound: estrogen deficiency worsens insulin resistance, which is further exacerbated by the age-related increase in cortisol that promotes gluconeogenesis

In those cases, addressing estrogen and other hormones more directly may be necessary