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Daisuke Tanaka (National Agriculture and Food Research Organization) for discussion on the cryopreservation mechanisms and Sayuri Yamagishi (Hirata Laboratory) for her technical assistance

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Dixon SJ, Patel DN, Welsch M, Skouta R, Lee ED, Hayano M et al (2014) Pharmacological inhibition of cystineglutamate exchange induces endoplasmic reticulum stress and ferroptosis

Specifically, it seemed that BPC-157 could regulate the phosphorylation level of extracellular signal-regulated kinases 1 and 2 (ERK1/2)

Increased oxidative damage to DNA in ALS patients

It's a purely physical reaction, not necessarily an inflammatory or allergic one