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This interaction triggers c-Met phosphorylation and activates downstream signaling cascades including the PI3K/AKT and MAPK/ERK pathways, which are fundamental to neuronal survival, dendritic arborization, and synapse formation

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While current immune checkpoint blockade therapies target PD-L1 at the cell surface, intracellular reservoirs of PD-L1 and its recycling to the plasma membrane have emerged as potential mechanisms of therapeutic resistance

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La prise au cours d'un repas contenant des graisses peut optimiser l'absorption des phospholipides liposomaux