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Two randomized control clinical trials reported conflicting effects on bone mineral content (BMC) and bone mineral density (BMD): one trial demonstrated preservation of BMC with GLP-1 use, while the other found no significant difference in BMC or BMD between treatment and control groups

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The safety profile of semaglutide 2.4 mg in STEP 5 was consistent with that in other STEP program trials 6,7,9,16,23 , and with the GLP-1 receptor agonist class in general 28

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In addition, peptide therapy in general may lead to side effects related to the route of administration, which, in the case of ipamorelin, is subcutaneous injection

Learn from Jillian, in person at Luminescence, our first Womens Health & Longevity Summit, in Los Angeles on February 1, 2025