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A plausible explanation may be that in these diseases, EHH symptoms prevent pancreatic cells from over-expressing this receptor

The EMA said that exposure to semaglutide in people with diabetes is linked to a twofold increase in the risk of developing NAION compared with people not taking the medicine

Consequently, manipulating the effects of GLP-1 has been seen as having interesting potential as a therapeutic target in type 2 diabetes

A licensed prescriber can evaluate clinical appropriateness

PMID: 18074940 Pandol S.J, Gorelick F.S, Gerloff A, Lugea A