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A study of humans with a genetic mutation for CYP2R1, or those done using CYP2R1 knockdown mouse models, demonstrate low circulating levels of 25(OH)VD 3 24
This forms an iron-LRRK2 positive feedback loop that exacerbates dopaminergic neuron apoptosis (163)
Shah, R., Farmer, L
Furthermore, it modulated blood metabolic parameters and positively influenced the hematological profile (RBCs, WBCs, and erythrocytes)
If you are strictly taking glutathione but your diet is lacking in minerals, you might not see the full range of benefits