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Reports of stability in gastric juice are not the same as systemic bioavailability, and routes of administration in published rodent work include intraperitoneal, oral (drinking water), and topical comparisons across routes are not always controlled in primary studies (Cerovecki et al., 2010)

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Therefore, examining mTOR pathway suppression by targeting GPX4 can provide further mechanistic insight into mTOR pathway signaling as a potential therapeutic target for advanced thyroid cancers

Kurosawa, K., Hayashi, N., Sato, N., Kamada, T

Cell Reports Medicine