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Obesity Science & Practice, 3 (1), 314
Clinical summary, 2025
[3] Neutral endopeptidase 24.11 (NEP 24.11) is a membrane-bound zinc metallopeptidase widely expressed in several tissues, but found in particularly high concentrations in the kidneys, which is also identified accountable for the rapid degradation of GLP-1
The problem is not that these formulations fail to deliver the drug
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However, that slowdown also means food sits around in your gut longer, giving bacteria even more time to break it down and release hydrogen sulfide gas
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